Light & health

Life Science / Sunled / January 24, 2022

We humans need visible light to see the world around us, to enjoy the beauty of nature or arts and to do our job. Moreover, we don't only need light to see, but light is also very important for our health. Both the visible and invisible parts of the solar spectrum affect our physical and mental health. Indoors, both the visible and invisible light are of much lower quality compared to outdoors. Indoors, most invisible parts of the solar spectrum are completely absent (Figure 1) and the visible light intensity is much lower. European office standards require 500 lux,1,2 while outdoor light levels easily exceed 50 000 lux.3

For a long time, indoor lighting’s only purpose was task lighting. In this case, light intensities should just be high enough to see what you are doing. However, recent biological research has shown us that light has many more purposes than just making us see. Insights from the early 2000’s have taught us that non-image forming (or ‘non visual’) photoreceptors in our eyes play a pivotal role in our circadian rhythm, hormonal cycles, and behavioral systems.4–6 Too low light intensities during the day, or too high light intensities during the night, have truly disruptive effects on human health and well-being. These insights are leading to increased awareness about the importance of high quality light in the built environment,7–9 with the Good Light Group10 as one of its main advocates.  

Figure 1. Normalized solar spectrum compared to normalized warm white LED spectrum, the most used light source of indoor illumination. The comparison of the spectra shows that large parts of the solar spectrum are absent in indoor illumination.

Light treatment

Bright light exposure during the day is an effective treatment against depression, and bright light exposure combined with dawn simulation is effective against seasonal affective disorder.11 Bright light exposure is also used as a treatment for sleep and circadian disturbances in patients with Alzheimer’s disease12 and to help shift-workers adapt their schedules and improve their sleep quality.13 Moreover, specific (visible) wavelengths can have beneficial effects as well, like blue pulses in the morning to improve the circadian rhythm,14 blue-enriched white light to improve alertness,15 or red light to increase day-time performance.16

Beyond visible light

Wavelengths outside the visible part of the solar spectrum have also been shown to have health effects on our body. UV radiation for example stimulates vitamin D and endorphin production, however it also induces aging and increased risks on several skin cancers17 so care should be taken with exposure to this kind of radiation.

Another invisible part of the solar spectrum is the near-infrared-region (roughly 700 – 1400 nm). This region too is absent in indoor illumination yet has all kinds of positive effects on the human body. Referred to as ‘photobiomodulation’ (PBM) a variety of positive effects of exposure to near-infrared (NIR) light has been reported, varying from neurological effects to physical effects. For example, treatment of retinal diseases,18 prevention and treatment of oral mucositis,19,20  promotion of wound healing,21 bone repair,22 Parkinson’s disease,23 and major depressive disorder.24 This led to development of specialty devices for home treatments and medical devices for professional use, but so far not to integration in general illumination devices.

Human centric lighting

An overwhelming body of scientific evidence is published about the importance of good light quality for human health and well-being, and slowly this message is taken up by the large lighting companies. Under the label ‘human centric lighting’, lighting products are being sold that are dimmable and adjustable in color temperature (CCT) and claimed to ‘not disturb the circadian rhythm’. However, the light intensities of these products are still far below natural light, and the complex interplay between color temperature, specific wavelengths, and light intensity is still not completely understood, making it difficult to assess the actual beneficial effects.25

Seaborough’s SunLED technology

Seaborough’s SunLED technology can make a true difference for people that spend their lives indoors. Clinical trials26 showed that our SunLED technology significantly reduces resting heart rate and boosts the immune system of users. These results will be published in a scientific journal in 2022. These significant effects show that we can effectively improve human health and well-being with everyday lighting products, as our SunLED technology integrates beneficial near-infrared radiation in every contemporary lighting design.

References

  1. The European standard NEN 12464-1 in a few key points https://www.any-lamp.com/blog/european-standard-nen-124641. Visited December 2021.
  2. Standard EN 12464-1 in brief https://www.fagerhult.com/knowledge-hub/EN-12464-1/Lighting-of-indoor-workplaces/. Visited December 2021.
  3. Thorington, L. Spectral, Irradiance, and Temporal Aspects of Natural and Artificial Light. Ann. N. Y. Acad. Sci. 1985, 453 (1), 28–54. https://doi.org/10.1111/j.1749-6632.1985.tb11796.x.
  4. Provencio, I.; Rodriguez, I. R.; Jiang, G.; Hayes, W. P.; Moreira, E. F.; Rollag, M. D. A Novel Human Opsin in the Inner Retina. J. Neurosci. 2000, 20 (2), 600–605. https://doi.org/10.1523/jneurosci.20-02-00600.2000.
  5. Van Gelder, R. N. Non-Visual Ocular Photoreception. Ophthalmic Genet. 2001, 22 (4), 195–205. https://doi.org/10.1076/opge.22.4.195.2215.
  6. Berson, D. M.; Dunn, F. A.; Takao, M. Phototransduction by Retinal Ganglion Cells That Set the Circadian Clock. Science 2002, 295 (5557), 1070–1073. https://doi.org/10.1126/science.1067262.
  7. Schlangen, L. J. M.; Price, L. L. A. The Lighting Environment, Its Metrology, and Non-Visual Responses. Front. Neurol. 2021, 12 (March). https://doi.org/10.3389/fneur.2021.624861.
  8. Brown, T. M.; Brainard, G.; Cajochen, C.; Czeisler, C.; Hanifin, J.; Lockley, S. W.; Lucas, R. J.; Munch, M.; O’Hagan, J.; Peirson, S.; Price, L.; Roenneberg, T.; Schlangen, L. J. M.; Skene, D.; Spitschan, M.; Vetter, C.; Zee, P.; Wright Jr., K. Recommendations for Healthy Daytime, Evening, and Night-Time Indoor Light Exposure. Preprints 2020, December, 1–21. https://doi.org/10.20944/preprints202012.0037.v1.
  9. Boyce, P. R. Review: The Impact of Light in Buildings on Human Health. Indoor Built Environ. 2010, 19 (1), 8–20. https://doi.org/10.1177/1420326X09358028.
  10. Good Light Group https://www.goodlightgroup.org/.
  11. Golden, R. N.; Gaynes, B. N.; Ekstrom, R. D.; Hamer, R. M.; Ph, D.; Jacobsen, F. M.; Suppes, T.; Ph, D.; Wisner, K. L.; Nemeroff, C. B.; Ph, D. The Efficacy of Light Therapy in the Treatment of Mood Disorders: A Review and Meta-Analysis of the Evidence. Am. J. Psychiatry 2005, 162 (4), 656–662. https://doi.org/10.1176/appi.ajp.162.4.656.
  12. Mitolo, M. Effects of Light Treatment on Sleep, Cognition, Mood, and Behavior in Alzheimer’s Disease: A Systematic Review. Dement. Geriatr. Cogn. Disord. 2018, 46, 371–384. https://doi.org/10.1159/000494921.
  13. Richter, K.; Acker, J.; Adam, S.; Niklewski, G. Prevention of Fatigue and Insomnia in Shift Workers — a Review of Non-Pharmacological Measures. EPMA J. 2016, 7 (16). https://doi.org/10.1186/s13167-016-0064-4.
  14. Geerdink, M.; Walbeek, T. J.; Beersma, D. G. M.; Hommes, V.; Gordijn, M. C. M. Short Blue Light Pulses (30 Min) in the Morning Support a Sleep-Advancing Protocol in a Home Setting. J. Biol. Rhythms 2016, 31 (5), 483–497. https://doi.org/10.1177/0748730416657462.
  15. Viola, A. U.; James, L. M.; Schlangen, L. J. M.; Dijk, D. Blue-Enriched White Light in the Workplace Improves Self-Reported Alertness, Performance and Sleep Quality. Scand. J. Work. Environ. Health 2008, 34 (4), 297–306.
  16. Sahin, L.; Wood, B. M.; Plitnick, B.; Figueiro, M. G. Daytime Light Exposure: Effects on Biomarkers, Measures of Alertness, and Performance. Behav. Brain Res. 2014, 274, 176–185. https://doi.org/10.1016/j.bbr.2014.08.017.
  17. D’Orazio, J.; Jarrett, S.; Amaro-Ortiz, A.; Scott, T. UV Radiation and the Skin. Int. J. Mol. Sci. 2013, 14 (6), 12222–12248. https://doi.org/10.3390/ijms140612222.
  18. Geneva, I. I. Photobiomodulation for the Treatment of Retinal Diseases: A Review. Int. J. Ophthalmol. 2016, 9 (1), 145–152. https://doi.org/10.18240/ijo.2016.01.24.
  19. Zecha, J. A. E. M.; Raber-Durlacher, J. E.; Nair, R. G.; Epstein, J. B.; Sonis, S. T.; Elad, S.; Hamblin, M. R.; Barasch, A.; Migliorati, C. A.; Milstein, D. M. J.; Genot, M. T.; Lansaat, L.; van der Brink, R.; Arnabat-Dominguez, J.; van der Molen, L.; Jacobi, I.; van Diessen, J.; de Lange, J.; Smeele, L. E.; Schubert, M. M.; Bensadoun, R. J. Low Level Laser Therapy/Photobiomodulation in the Management of Side Effects of Chemoradiation Therapy in Head and Neck Cancer: Part 1: Mechanisms of Action, Dosimetric, and Safety Considerations. Support. Care Cancer 2016, 24 (6), 2781–2792. https://doi.org/10.1007/s00520-016-3152-z.
  20. Zadik, Y.; Arany, P. R.; Fregnani, E. R.; Bossi, P.; Antunes, H. S.; Bensadoun, R.-J.; Gueiros, L. A.; Majorana, A.; Nair, R. G.; Ranna, V.; Tissing, W. J. E.; Vaddi, A.; Lubart, R.; Migliorati, C. A.; Lalla, R. V.; Cheng, K. K. F.; Elad, S. Systematic Review of Photobiomodulation for the Management of Oral Mucositis in Cancer Patients and Clinical Practice Guidelines. Support. Care Cancer 2019, 27, 3969–398398. https://doi.org/doi.org/10.1007/s00520-019-04890-2.
  21. Kuffler, D. P. Photobiomodulation in Promoting Wound Healing: A Review. Regen. Med. 2016, 11 (1), 107–122. https://doi.org/10.2217/rme.15.82.
  22. Escudero, J. S. B.; Perez, M. G. B.; de Oliveira Rosso, M. P.; Buchaim, D. V.; Pomini, K. T.; Campos, L. M. G.; Audi, M.; Buchaim, R. L. Photobiomodulation Therapy (PBMT) in Bone Repair: A Systematic Review. Injury 2019, 50 (11), 1853–1867. https://doi.org/10.1016/j.injury.2019.09.031.
  23. Salehpour, F.; Hamblin, M. R. Photobiomodulation for Parkinson’s Disease in Animal Models: A Systematic Review. Biomolecules 2020, 10 (4), 1–19. https://doi.org/10.3390/biom10040610.
  24. Cassano, P.; Petrie, S. R.; Hamblin, M. R.; Henderson, T. A.; Iosifescu, D. V. Review of Transcranial Photobiomodulation for Major Depressive Disorder: Targeting Brain Metabolism, Inflammation, Oxidative Stress, and Neurogenesis. Neurophotonics 2016, 3 (3), 031404. https://doi.org/10.1117/1.nph.3.3.031404.
  25. Circadian-Friendly Light Emitters: From CCT-Tuning to Blue-Free Technology https://www.led-professional.com/resources-1/articles/circadian-friendly-light-emitters-from-cct-tuning-to-blue-free-technology. Visited December 2021.
  26. PBM for health and wellbeing : https://trialsearch.who.int/Trial2.aspx?TrialID=NL8800  Visited December 2022.